Cleaning Application Font Caches
Adobe products, QuarkXPress 6.5 and Microsoft Office keep their own font cache files. To ensure best performance and stability of these applications, you should clean the cache files regulary.
Choose Tools > Clean application font caches...
Select the applications you want to clean the caches for.
Click "Clean...".
Cleaning the application caches for QuarkXPress 7.0 is not necessary.