Simmons College
Department of Chemistry
Chemistry 225: Organic Chemistry II
Fall 1999
Professor Nancy E. Lee
Office: S-440 Tel: 521-2732
Office Hours: Thurs. 12:00-1:30; Fri. 9-10:30
Study Group: Wed. 4-6 in room S432
e-mail address: nlee@simmons.edu
Chem. 225 web site address: http://www.simmons.edu/~lee/
Texts and Required Materials
:Fessenden & Fessenden, Organic Chemistry, 6th Ed.,(Brooks/Cole, 1998).
Fessenden & Fessenden, Solutions Manual, 6th Ed.,(Brooks/Cole, 1998).
Molecular model set
Laboratory notebook with numbered pages
A pair of safety glasses.
Exams: There will be one take-home exam and three in-class exams and a final. Three out of four exams will be counted toward your grade. The lowest exam score will be dropped at the end of semester. If you miss an exam, you will receive zero for the exam. The dates of these exams are as follows:
Exam I (take-home) Sept. 22, 1999 (due date)
Exam II Oct. 6, 1999
Exam III Oct. 29, 1999
Exam IV Nov. 19, 1999
Final TBA
Quizzes: There will be a total of 8 weekly quizzes this semester. The quizzes will be given from 10:30-10:40 on Fridays or Mondays; be sure to come to class on time (see unit syllabus for exact dates of the quizzes). The quizzes will cover the previous week’s reading, homework assignments, and lecture notes. 7 out of 8 quizzes will be counted toward your grade and the lowest quiz will be dropped at the end of the semester. If you miss a quiz (due to absence or being late to class) you will receive zero for the quiz. There will be no make-up quizzes given this semester.
Homework: During the term, reading assignments and homework problems from F&F will be assigned for each lecture. (NOTE: All the homework assignments must be done in a bound notebook.) It is your responsibility to work on these problems - they will not be collected. However, if you receive an academic warning from this class, you will be required to hand in your homework notebook at the end of semester.
You should work on the assigned problems on your own, attempting them before looking up the answers! In addition, a review problem set will be handed out for each unit a few days before each exam. Solutions to the problem set will be discussed in the study groups or review sessions and the answers will be on my web site.
Attendance: It is extremely important that you attend all the classes. Keeping up with the enormous amount of new material presented in each lecture is the key to success in this course. It is much more difficult to keep up if you miss classes. However, if you do miss a class due to illness, it is your responsibility to obtain the notes and handouts that you missed from a classmate.
Study Group: It is highly recommended that you attend the study group that will be offered on a weekly basis. You should bring all your questions (from lecture, from homework problems, from labs etc..) to the study group.
Study Group Time & Place: Wednesdays 4-6 in room S432
Office Hours: There will be three hours designated as office hours per week. You are encouraged to come in during these hours to ask any questions. If your schedule conflicts with the study groups and office hours, you should make individual appointments to see me by phone or e-mail. If you can not keep the appointment, please let me know in advance.
Weekly office hours: Thurs. 12:00-1:30; Fri. 9-10:30
Advice
: You should plan to spend at least 10-12 hours a week for this class. You will be presented with a lot of new material in each lecture. Pay attention and take good notes during the lectures. After each lecture, try to understand the concepts presented by studying your notes and assigned readings. Once you feel that you've mastered the concepts, try the homework problems. It may be helpful to study in groups so that you can talk to others about homework problems, lectures and labs etc. Students also find taking notes from reading assignments and using 3x5 index cards to be extremely helpful. The key to success in this class is to keep up with the fast pace of the class; cramming right before exams will not work! Since each lecture has homework problems and reading assignments, you should do the work before the next class. The next lecture will build on the previous lecture and I will assume that you have understood the material from the previous lecture. Procrastination is the biggest source of failure in organic chemistry!Grades:
3 best out of 4 Exams (100 pts each) 300 pts
Final Exam 250 pts
6 best out of 8 Quizzes ( 25 pts each) 150 pts
Laboratory Grade 300 pts
___________________
Total 1000 pts
Chemistry 225: Organic Chemistry II
Fall 1999 Tenative Syllabus and Lecture Outline
Unit # |
Topic |
Lecture # |
Dates |
Unit I |
Review of Organic Chemistry I and Spectroscopy: Review of hybridization, resonance, stereochemistry; acid-base chemistry, substitution and elimination reactions, and alkene chemistry. Introduction and interpretation of 1H NMR and IR. Exam I (take-home) : due 9/22/99 @ 10:30 A.M. |
1-6 |
9/3-9/17 |
Unit II |
Chemistry of Aldehydes and Ketones: Review of alcohol chemistry; Grignard Reaction; Addition reactions including ketal, Wittig, and imine synthesis. Exam II: Oct. 6, 1999 |
7-12 |
9/20-10/1 |
Unit III |
Chemistry of Carboxylic Acids and Derivatives: Chemistry of carboxylic acids and acid derivatives including anhydrides, acid halides, esters, lactones, amides and nitriles. Chemistry of Amines: Basicity and substitution reactions of amines Exam III: Oct. 29, 1999 |
13-20 |
10/4-10/25 |
Unit IV |
Enolate Chemistry: Carbon-carbon forming reactions of enols and enolate anions. Aldol and Claisen reactions. Michael reactions. Synthetic strategies. Exam IV: Nov. 19, 1999 |
21-28 |
10/27-11/15 |
Unit V |
Bioorganic Chemistry: Sugars, carbohydrates, lipids, amino acids, peptides, proteins and nucleic acids. Final Exam: TBA |
29-35 |
11/17-12/8 |